Looking for males and females ages 18-65 with high blood pressure to volunteer for a 6 month blood pressure research study. You will go off your present blood pressure medication for 4 weeks and then be placed on either hydrochlorothiazide (HCTZ) or atenolol for 18-24 weeks. Remuneration offered. This study is being performed to help determine whether or not measurements of genetic variation might help predict a patient’s response to a particular blood pressure medication. If interested please call Ruth Kraft 266-8133 or Tyson Scrabeck 266-8302 or e-mail kraft.ruth@mayo.edu ; scrabeck.tyson@mayo.edu